Jeff Lichtmann just did a TED talk at connetomics at Caltech that is really worth a watch if you are interested in Connectomics. A couple of weeks ago he gave a longer version of the same talk here at the MPI in Tübingen. I think it does a fantastic job of defining why someone would be interested in “Connectomics”, presents an honest depiction of the magnitude of some of the technological problems involved, and, for me at least, leaves you with some hope that we can make big things happen by pursuing this approach. Something that comes across better in person than on YouTube are these amazing reconstructions where they have gone so far as annotate the positions of all of the synaptic vesicles. Strikingly beautiful! Nicely done talk that will get a lot of exposure, and I hope that it inspires more people to be doing this kind of work.